International Journal of Molecular Sciences (2018) 2
Glucagon-like peptide-1 (GLP-1) receptor agonists were originally developed to treat people with type 2 diabetes, entering clinical use in the mid-2000s
In the past, to lose weight, you needed to be under calorie restriction and you really needed to starve. The big change with GLP-1 is that you can eat normally and youre going to lose weight, so thats a big change. Monitoring will continue into, and probably beyond, 2026
"That was the first moment that I was like, holy cow, these insurance companies, they're now making medical decisions for me," she says
Cons of injectable semaglutide Requires selfinjection (which some people dislike)
For weight management, specialist services may prescribe specific formulations for adults with BMI of at least 35 kg/m (or 30 kg/m with weight-related comorbidities) and at least one weight-related condition