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Zhao WQ, De Felice FG, Fernandez S, et al

If the underlying gut dysfunction is never addressed, many of those symptoms can return after stopping the GLP-1

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The story starts 1906 with a report that an extract of intestinal tissue could lower blood glucose, but no progress was made toward purifying this factor

This combination of preference toward GIP receptor and distinct signaling properties at GLP-1 suggest this biased agonism increases insulin secretion

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