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In the STEP 1 and SUSTAIN 8 trials, around 40% of the weight lost was lean tissue
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However, this route requires clear clinical justification, appropriate prescriber documentation, and informed patient consent
This is particularly relevant in Canada, where metabolic syndrome prevalence has been rising steadily, especially in provinces with higher rates of sedentary lifestyles during long winter months
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![PDF] Glutathione peroxidases as oncotargets](https://figures.semanticscholar.org/1b1ef14a02462595e924be2e60829cfd23947470/3-Figure1-1.png)
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