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Combined treatments with anti-angiogenic agents (anti-VEGF or anti-VEGFR2) and ICB stimulated vessel normalization and the formation of HEV, favoring immune control of tumor progression (154, 155), and induced anti-tumor T cell responses (156)

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Vitamin C plays an important role in supporting the bodys antioxidant network

In wheat, overexpression of a spermidine synthase gene increased polyamine levels and improved resistance to Fusarium head blight without compromising yield, indicating that manipulation of spermidine metabolism can strengthen disease resistance in cereals 88