tirzepatide and irritability 💊 — Mechanism of Action & Pharmacokinetics 👨‍⚕️ Mechanism of Action • Tirzepatide is the first dual GIP/GLP-1 receptor agonist. • Activates both: - Glucose-Dependent Insulinotropic Polypeptide (GIP) receptors Retatrutide vs. Tirzepatide vs. Semaglutide

Move your body daily and include walking after meals to stimulate digestion

Alcohol and Caffeine: It is important to limit your alcohol and caffeine intake while taking Compounded GLP-1s

But your healthcare provider can guide you through the process

Hubel, C

Contact your healthcare provider immediately if you experience: Signs of pancreatitis severe, persistent abdominal pain (often radiating to the back), with or without vomiting Symptoms of gallbladder disease right upper abdominal pain, fever, jaundice (yellowing of skin or eyes) Severe dehydration or signs of acute kidney injury decreased urination, extreme thirst, dizziness, confusion, or rapid heartbeat Hypoglycemia symptoms (especially if taking insulin or sulfonylureas) shakiness, sweating, confusion, rapid heartbeat Any sudden vision changes blurred vision or other visual disturbances Allergic reactions difficulty breathing, facial swelling, severe rash, or hives (seek emergency care immediately) Signs of thyroid tumors neck lump, persistent hoarseness, difficulty swallowing, or shortness of breath Patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 should not use Zepbound, as tirzepatide carries a boxed warning regarding thyroid C-cell tumors observed in animal studies

The primary outcome was a new diagnosis of SIBO following GLP-1 RA exposure