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290,291,292 Accumulating macrophages release cytokines and chemokines, including IL-1, IL-6, chemokine ligand 2 (CCL2), and TNF-, intensifying the inflammatory environment and aggravating nerve damage
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Anti-inflammatory supplements can provide meaningful relief
While improvements in diet and physical activity might explain some of the overall improvement, they do not account for the differences observed between the active and placebo groups
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