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Ostrerova-Golts, N

Dimethyl fumarate is currently the only Nrf2 activator with FDA approval for the treatment of multiple sclerosis but is also associated with desensitization and other side effects (Gold et al

All these suggest that hepatocytes may downregulate the expression of HNF4 in an injured liver, which promote the EMT of hepatocytes and contribute to the fibrosis process (100)

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doi:10.1007/s12325-019-00914-9 40

Subjective evaluation of skin properties For global evaluation, at each visit, subjects were asked to grade the overall response using a 4-point rating scale: 4 = very satisfactory, 3 = moderately satisfactory, 2 = minimally satisfactory, and 1 = not satisfactory