Knowing what to expect based on the clinical trial literature helps distinguish between expected effects and anomalies that warrant investigation
[98] [100] [101] Several applications and approvals for generic semaglutide followed, both for type 2 diabetes [94] and weight loss
If maintenance dose data supports it, a long-term strategy might look like this: titrate to 8-12mg for 48-68 weeks of active weight loss, then step down to 4-6mg for indefinite maintenance
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Zhang Y, Zhang Q, Bai Y, Zheng H, Ji L, Zhu X et al (2023) Glycogen synthesis kinase-3 involves in the analgesic effect of liraglutide on diabetic neuropathic pain