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The oncogenic transcription factor c-Jun is reported to elevate the expression of mitochondrial glutaminase by directly binding to its promoter region in breast cancer cells [12]

preparing (R)-4-chloro-3-hydroxy butyric acid alkyl ester of Formula 4 from stereoselective hydrolysis of the racemic 4-chloro-3-hydroxy butyric acid alkyl ester of Formula 3 in an aqueous solution using an enzyme or an enzyme- containing microorganism

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