Serious adverse events are rare and usually manageable through dose titration or supportive care
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For example, a small number of subjects reported the following mild side effects in the course of a four-week glutathione study at the dose of 1g/day [13]: Flatulence Loose stools Flushing Weight gain In a more specialized study involving cystic fibrosis patients and much higher glutathione doses, some of the patients reported tightness in the torso, diarrhea, and fever-like symptoms [14]
Reinforces ongoing cellular defense mechanisms
Furthermore, SLC3A1 upregulation has been demonstrated to promote breast cancer growth through cysteine uptake (49)