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The results showed that while both medications led to weight loss, semaglutide was more effective and had a lower frequency of side effects compared to liraglutide, particularly nausea and vomiting
Another study found hemoglobin A1C was found to be suppressed
Though they may have risks, compounded drugs are still useful for many people
Clinical trials did not identify changes in sexual function as a significant adverse event associated with liraglutide treatment
Mechanistically, this complementarity is plausible: while surgery provides mechanical gastric restriction and alters gut hormone profiles, its inability to fully correct the underlying energy homeostasis dysregulation in MC4R deficiency often leads to long-term weight regain [43,45]
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