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Importantly, constipation severity varies considerably among individuals
Guidance on good manufacturing practice and good distribution practice questions and answers (EMA)
In clinical trials, participants lost approximately 15% of their body weight at the 5 mg dose and about 20% at the 15 mg dose over 72 weeks in the SURMOUNT-1 trial
Moreover, the excessive release of NETs can lead to tissue damage and trigger inflammation (32)
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