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GSH depletion causes oxidative stress and lipid peroxidation To evaluate the downstream effects of GSH depletion, we measured soluble ROS in RPE cells treated with Cys 2 starvation, BSO, or erastin by flow cytometry using the fluorescent probe H 2 DCFDA

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It captures chronic, lingering inflammation rather than acute spikes

A role of the enzyme in modulating stress responses by controlling JNK activity was also proposed 56, 57

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Self-directed supplementation without medical oversight may complicate diabetes management or obscure the assessment of tirzepatide's therapeutic effects