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MAFLD is characterized by the abnormal accumulation of fat (steatosis) in the liver in the absence of heavy alcohol consumption and in the presence of obesity, type 2 diabetes mellitus, or metabolic dysregulation (92)

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The homocysteine produced can be either remethylated to methionine or condensed with serine to form cystathionine

andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, et al

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Cooper highlights transformative new science, and Andrea brings personal experience that challenges stereotypes and reveals the harm of shame-based approaches