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This conservative approach has merit because it keeps a higher dose in reserve as a strategic tool

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Reconstitution: For laboratory research applications, qualified personnel must handle this material under aseptic conditions

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The 50 mg/kg figure is animal-research dosing only

Because GLP-1 cannot be deleted specifically without affecting the other products of the proglucagon gene including glucagon, attention has focused on the GLP-1 receptor gene which can be deleted independent of the glucagon receptor