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doi: 10.1016/j.bbrc.2017.06.031 150 MeierJJGoetzeOAnstippJHagemannDHolstJJSchmidtWEet al

Wilkinson, J

The PRAC assesses the protocols (aspects related to the organisation of a study) and the results of PASSs

Short-Acting Versus Longer-Acting Patterns After abrupt cessation of short-acting opioids such as heroin , hydrocodone , and oxycodone , symptoms typically begin within 8 to 12 hours after the last dose, peak around 36 to 72 hours , and then taper over roughly 4 to 7 days