If truly non-responsive to GLP-1 therapy, non-GLP-1 alternatives like phentermine-topiramate or the upcoming amylin-based therapies work through different mechanisms that may be more effective for your specific biology
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Serum levels, however, may be high, low or normal and are therefore unreliable as an indicator of L-carnitine metabolism [22]
A patient who is already on semaglutide, in other words, may not be on a MASH-approved dose, even though lower doses may still provide metabolic or liver-related benefit
Fluids, fiber, and timing help prevent this
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