PMID: 16962140 DOI: 10.1016/j.jns.2006.06.007 Keywords Soman (GD) Drug Class: Organophosphate Chemical Warfare Agent classified as a Nerve Agent Mechanism of Action: Inhibits the destruction of acetylcholine by cholinesterase Aging occurs within a half-life of only 2 minutes with soman Rapid aging can make it almost impossible to give pralidoxime rapidly enough to be beneficial after the first noticeable detection of symptoms of poisoning are felt, at which point a significant degree of aging has already occurred
(Note: the 3ml/cc mixing syringe will need to be filled several times to transfer all the fluid into the powder) Insert needle into hCG vial (alcohol wiped) and inject water slowly into hCG powder Gently swirl the vial around until solution is clear
DSIP is a nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, molecular formula CHNO, and a molecular weight of 848.81 Da
9:e15402
Preparation Condition 4 (EDTA 4 o C deproteinization): Storage temperature affects total GSH, free GSH, and GSSG, but not the ratio of free GSH to GSSG in plasma We included EDTA-treated plasma stored at 4 o C (Preparation Condition 4) as a positive control for enzymatic degradation of glutathione which may occur during sample storage
Many medical professionals prescribe the so-called RICE therapy of rest, ice, compression, and elevation