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Discovered in 2015 by Changhan David Lee and Pinchas Cohen at USC, MOTS-c is encoded in the 12S rRNA region of the mitochondrial genomemaking it one of a small but growing family of mitochondrial-derived peptides (MDPs) that challenge the longstanding view of mitochondria as passive energy factories

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Indian J Clin Biochem 36(4):416426 Daz M et al (2019) Synthesis and leishmanicidal activity of novel urea, thiourea, and selenourea derivatives of diselenides

Tirzepatide delivered more than double that in its mid-range dose and nearly triple it at the highest dose

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