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Projections indicate regain plateaus at 75% of lost weight.[4][8][9][2] Physiological Mechanisms Behind Regain The body defends its set point weight through adaptive responses
Or as a 1998 New England Journal of Medicine editorial summarized: we should remember that the cure for obesity may be worse than the condition. Cultural and clinical attitudes toward obesity have since shifted
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PMID: 11157478
Metabolism 24 (8), 15531564
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