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Fatty acids (FAs) have therapeutic potential by stimulating GLP-1 secretion
Ipamorelin works through a different receptor pathway that triggers GH release more directly
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In that study, the glucose-sensing transcription factor carbohydrate response element binding protein (ChREBP) has been shown to initiate a regulatory program driving an early transcriptional activation of metabolic genes, which is followed by a second wave of transcriptional regulation wherein cell-cycle genes are activated and -cell identity genes are repressed
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