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Vitamin E protects against lipid peroxidation and rescues tumorigenic phenotypes in cowden/cowden-like patient-derived lymphoblast cells with germline SDHx variants
We treated 10- to 12-week-old male sAC / mice with intrajugular 3.6 mol/kg GLP-1(2836) versus the scrambled control 30 minutes prior to standard open-chest IRI involving a 45-minute LAD occlusion
Vinicius Cruzat, Marcelo Macedo Rogero, Kevin Noel Keane, Rui Curi, Philip Newsholme (2018 Oct) Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation
This paper reviews the most relevant experimental studies that have contributed to a better understanding of the molecular mechanisms and intracellular pathways involved in cardioprotection induced by GLP-1 and analyzes in depth its potential role as a therapeutic target both in the ischemic and reperfused myocardium and in other conditions that are associated with myocardial remodeling and heart failure
This is a secondary effect of overall matrix improvement, not a direct pore-targeting action