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[1] The authors reported that methylquinolinium analogs with primary-amine substitutions displayed high permeability from passive and active transport across membranes, measured using two standard in-vitro models: the parallel artificial membrane permeability assay (PAMPA) and Caco-2 human intestinal cell monolayers

The peptide does not cause fluid retention that would register as weight gain

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weight outcomes were modest and inconsistent, and development for obesity treatment was not continued