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Cagrilintide is structurally derived from amylin/calcitonin family peptides with multiple modifications
Evidence from single-cell transcriptomics indicates that in VIP interneurons of ASD patients brains, transcription factors such as Abelson Helper Integration Site 1 (AHI1) and synaptic genes like RAS-Associated Protein RAB3A (RAB3A) are downregulated
Advanced Science
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2016;4(1):e1184775 Kitraki E
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![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)