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Glutathione metabolism and its implications for health
On absorption in the small intestine, bile acids activate the nuclear farnesoid X receptor in enterocytes, which stimulates production and release of fibroblast growth factor 19 (FGF19)
Elevated ROS reinforce TGF-/Smad signaling, driving hepatic stellate cell transdifferentiation into myofibroblasts and fibrogenesis [414]
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Enzymatic activities include superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT)
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