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After 56 weeks: Placebo group lost 1.6% of body weight Starting dose (3.75/23 mg) group lost 5.1% of body weight Top dose (15/92 mg) group lost 10.9% of body weight Beyond weight loss, the CONQUER trial showed significant improvements in blood pressure, waist circumference, lipid profiles, glycemic parameters, and inflammatory biomarkers compared to placebo

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For those preferring direct glutathione supplementation, liposomal or acetyl-glutathione formulations may offer theoretical advantages over standard reduced glutathione, though the clinical significance of these differences remains uncertain

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doi: 10.1038/S41574-019-0280-9 47 HompeschMJones-LeoneACarrMCMatthewsJZhiHYoungMet al