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It also allows for individual insight, which can only be gained from comparing cycle patterns before and after starting GLP-1 medications
Compound 7J was found to have the best ferroptosis inhibitory activity by SAR study, 7J showed good ROS scavenging ability and could alleviate DOX-induced cardiotoxicity with a good pharmacokinetic profile and no significant toxicity in vitro and ex vivo (You et al., 2022)
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Contact your GP, diabetes team, or NHS 111 if nausea significantly interferes with eating, drinking, or daily activities

Metabolic rebound after GLP-1 reception agonist discontinuation This new meta-analysis compiled data from 18 studies (3771 participants) to establish the effects of discontinuing use of GLP-1 receptor agonists on metabolic outcomes Here are the main findings In adults with obesity, discontinuing GLP-1 receptor agonists use led to significant Weight regain (+5.63 kg) Increase in HbA1c (+0.25%) Plus increased waist circumference, BMI, systolic blood pressure and fasting plasma glucose In adults with diabetes, discontinuing GLP-1 receptor agonists use led to significant Weight regain (+2.03 kg) Increase in HbA1c (+0.65%) Weight regain was also greater with a longer follow-up period, indicating that weight regain continues to rise the longer the period of discontinuation This meta-analysis highlights key aspects of GLP-1 receptor agonist use: 1 GLP-1 receptor agonists use may only be a long term strategy to support weight loss (if you start, you stay using it) 2 You must combine GLP-1 receptor agonists use with behavioural interventions to support weight loss outcomes (diet and exercise) 3 You cannot rely of GLP-1 receptor agonists alone over the short term, and expect to maintain any metabolic and/or weight loss outcomes Reference: Subscribe to Performance Nutrition Digest FREE to receive your daily study breakdown, straight to your inbox or via the Substack app Performance Nutrition Digest is powered by Healthspan Elite GLP-1 Receptor Agonist Discontinuation Effects on Metabolism Metabolic rebound after GLP-1 reception agonist discontinuation This new meta-analysis compiled data from 18 studies (3771 participants) to establish the effects of discontinuing use of GLP-1 receptor agonists on metabolic outcomes Here are the main findings In adults with obesity, discontinuing GLP-1 receptor agonists use led to significant Weight regain (+5.63 kg) Increase in HbA1c (+0.25%) Plus increased waist circumference, BMI, systolic blood pressure and fasting plasma glucose In adults with diabetes, discontinuing GLP-1 receptor agonists use led to significant Weight regain (+2.03 kg) Increase in HbA1c (+0.65%) Weight regain was also greater with a longer follow-up period, indicating that weight regain continues to rise the longer the period of discontinuation This meta-analysis highlights key aspects of GLP-1 receptor agonist use: 1 GLP-1 receptor agonists use may only be a long term strategy to support weight loss (if you start, you stay using it) 2 You must combine GLP-1 receptor agonists use with behavioural interventions to support weight loss outcomes (diet and exercise) 3 You cannot rely of GLP-1 receptor agonists alone over the short term, and expect to maintain any metabolic and/or weight loss outcomes Reference: Subscribe to Performance Nutrition Digest FREE to receive your daily study breakdown, straight to your inbox or via the Substack app Performance Nutrition Digest is powered by Healthspan Elite To view or add a comment, sign in More Relevant Posts Vitamin B12 Deficiency Definition: Vitamin B12 deficiency is a condition caused by insufficient vitamin B12, leading to impaired DNA synthesis, megaloblastic anemia, and neurological dysfunction
