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Cureus , 16(9), e70279.
1,2 As previously noted, when adding a GLP-1 RA to established background basal insulin therapy, adjustment of the background insulin is often necessary to avoid hypoglycemia
Philadelphia: The Pew Charitable Trusts
Safety Profile: Clinical Evidence for Combined Use Published clinical trials examining GLP-1 medications in patients with hypothyroidism have not identified contraindications or serious drug interactions between semaglutide and levothyroxine
But for patients without easy access to lab work, it's a meaningful value-add that partially justifies the higher monthly cost
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