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Although ACTL6A has been characterized as an oncogene in many human cancers, its role in GC is unknown, and knowledge of the underlying mechanisms is limited

In addition, PCOS has implications beyond reproductive issues, including infertility, miscarriage, and neonatal and pregnancy complications, but also increases the risk of psychological disorders including depression, cardiovascular disease including coronary atherosclerotic heart disease, and metabolic disorders including diabetes (1, 2)

This is a fundamental principle of translational pharmacology

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