Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma
How it was discovered: Scientists studying stomach ulcers noticed a particular protein sequence that protected the gut lining
Michaloglou C, Vredeveld LC, Mooi WJ, Peeper DS
Suppliers use the two labels interchangeably
A critical role of the IL-1-IL-1R signaling pathway in skin inflammation and psoriasis pathogenesis
This article summarises the position reached with the GLP-1 RAs and reviews the developing field of unimolecular co-agonists that act not only on the GLP-1 receptor, but on other receptors, notably glucose-dependent insulotropic polypeptide (GIP) and glucagon receptors, with the aim of further improving glycaemic control and weight reduction