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PubMed American Society of Health-System Pharmacists

Clinical trials for these treatments have consistently highlighted digestion challenges as the most prevalent side effects clinical studies for Wegovy PI, for example, showed 44% of patients suffered nausea (compared to 16% in the placebo group)

Respiratory symptoms including difficulty breathing or chest tightness are rare but serious reactions requiring immediate medical attention

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GLP-1 medications are very effective at reducing calorie intake, so it may be especially challenging to eat less when you stop taking them