Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core bloodbrain barrier dysfunction module
133 Caspase-1 is a key effector molecule downstream of inflammasome activation and plays a central role in processing and releasing proinflammatory cytokines, such as IL-1 and IL-18
Frontiers In Cardiovascular Medicine 9:966968 Gibb AA, Murray EK, Eaton DM, Huynh AT, Tomar D, Garbincius JF, Kolmetzky DW, Berretta RM, Wallner M, Houser SR, Elrod JW (2021) Molecular signature of HFpEF: systems biology in a cardiac-centric large animal model
It should not be used if you are taking opioid medications, have a history of seizures, eating disorders, or are stopping alcohol or benzodiazepines abruptly
Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist
The GCGR component drives -oxidation and mitochondrial biogenesis in hepatocytes through a cAMP-PKA-PGC1 pathway that is independent of weight loss