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Capron A, Capron M, Dombrowicz D and Riveau G

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Eating regular, balanced meals even within a calorie deficit helps maintain saliva production and reduces the depth of ketosis

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A 2025 randomized, double-blind, placebo-controlled trial published in Clinical Nutrition found that 15 mg/day of hydroxytyrosol improved antioxidant and anti-inflammatory status in overweight individuals with prediabetes over 16 weeks, while preserving insulin sensitivity (Moratilla-Rivera et al., 2025)

Based on current clinical trials, the efficacy estimand for injectable semaglutide shows it leads to more significant body weight loss than today's oral tablets