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(Interestingly, hes found that increasing the very small amount formed in the nasal systems olfactory bulb seems to amplify the motivation to eat.) His hope is that eventually we will be able to activate very specific pathways in the brain using the drug, which would allow for more narrowly targeted pharmaceutical treatments

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Zhang J, Liu D, Zhang M, Zhang Y

As mentioned, DPP-4 inhibitors increase the concentration of endogenous GLP-1, leading to increased insulin secretion, decreased glucagon secretion, and decreased HbA1c in patients with T2DM

It has been shown to repair tissue damage, even that caused by prolonged corticosteroid use

Diabetes 43: 535-539, 1994