semaglutide for heart failure versus placebo in patients with and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials Semaglutide in Patients with Heart

Some people may notice a difference in their skin clarity or energy levels within a few weeks

Before starting Januvia, it is crucial to discuss any existing health conditions with your healthcare provider

In early human studies, weight reduction persisted beyond the last dose, which fits a drug that lingers and works gradually rather than spiking and crashing

When to contact your GP: Persistent or severe nausea/vomiting preventing adequate fluid intake Severe, persistent abdominal pain which could indicate pancreatitis New or worsening depression, anxiety, or suicidal thoughts Severe headaches or visual disturbances Unexplained cognitive changes or confusion Signs of hypoglycaemia (if taking alongside insulin or sulfonylureas) NICE guidance recommends regular monitoring during GLP-1 receptor agonist therapy

Kantor et al

Ive seen a steady 12 lb weight loss per week, and my post-meal crashes are gone