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Moreover, fatty acids can impair mitochondrial function, as high concentrations of FFAs cause mitochondrial membrane depolarization and activate the mitochondrial permeability transition pore related to mitochondrial calcium overload

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1 A separate two-year extension followed participants with a BMI of 35 or higher who completed the main trial and tolerated their dose

Broccoli sprout extract prevents diabetic cardiomyopathy via Nrf2 activation in db/db T2DM mice

GLP-1 receptor agonist medications mimic this hormone at sustained therapeutic levels to treat type 2 diabetes and obesity

Phenols, such as hydroxytyrosol and oleuropein, have shown antioxidant properties in vitro and in vivo studies (Posadino et al., 2021)