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For topical formulations, concentrations of 0.1 to 0.3 percent are used, with efficacy detectable from as low as 0.01 percent
doi:10.1111/j.1651-2227.2005.tb01878.x
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What the Clinical Evidence Says About the Combination A randomized controlled trial published in the Journal of Cutaneous and Aesthetic Surgery comparing dermaroller monotherapy versus dermaroller combined with copper peptide for acne scars across 16 weeks produced findings that are clinically useful but deserve an honest reading
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