Jiang X, Liu B, Nie Z, Duan L, Xiong Q, Jin Z, et al
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Among those who stayed on treatment for the full 68 weeks, cagrilintide 2.4 mg delivered an average of about 12% body weight reduction , compared to 2.3% for placebo
This is exactly why the REDEFINE 4 trial exists
the SELECT cardiovascular trial enrolled over 17,000 more
GLP-1 receptors are expressed abundantly throughout the pancreas, and in response to GLP-1 therapy, the cells of the pancreas proliferate, swelling the organ, and potentially squeezing off ducts, causing inflammation, at least in rats