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This trial showed approximately 20% reduction in cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke compared to placebo
The mean body mass index was 35.3 (CI, 32.9-37.7) kg/m2
However, rapid weight reduction can lead to loss of both adipose tissue and lean muscle mass , including in the gluteal muscles (gluteus maximus, medius, and minimus)
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