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Poor sleep elevates cortisol, reduces growth hormone output, impairs insulin sensitivity, and increases appetite

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Biomed Pharmacother 143:112139

When compared to other GLP-1 medicationssuch as liraglutide (Saxenda), dulaglutide (Trulicity), and exenatide (Byetta)semaglutide generally leads to more pronounced and sustained weight loss outcomes

To assess this, randomized trials typically evaluate the primary outcome of major adverse cardiovascular events (MACE), which includes cardiovascular death, non-fatal stroke, and non-fatal myocardial infarction (MI)

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