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Suzuki, Y., Sa, Q., Gehman, M

The key to remember is that low methylation equals low glutathione and that low glutathione slows methylation

doi: 10.1210/er.2002-0015 156 LamosEMMalekRDavisSN

[Platelet glutathione reductase and glutathione-S-transferase in elderly research [PMID: 34693693] Laboratory literature summary: [Platelet glutathione reductase and glutathione-S-transferase in elderly research subjects with depression]

PMID 24080311

Here is a summary of the most commonly used DSIP dosing protocol based on available reports: Starting DSIP dose: 100mcg administered at night, preferably three hours before bedtime