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Sixth, it is probable that real-world adherence to these medications would be lower than in the trials used to inform our study [9], although it should be noted that the scenario analyses with lower uptake did not substantially affect the ICER

In the trial groups of 1, 2, and 4, the individuals were instructed to limit their calorie intake and maintain a calorie deficit of 500 kcal per day

Any cloudiness or visible particles after the medication has reached room temperature are signs that the vial should be discarded

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It is important to identify individuals who have potential risk for adverse reactions that might make them ineligible for treatment with semaglutide