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The dominant adverse events in both are gastrointestinal nausea, diarrhea, vomiting, and constipation and in both they are dose-dependent and tend to ease as the body adapts to gradual dose escalation
Thyroid considerations GLP-1 receptor agonists carry a boxed warning about thyroid C-cell tumors based on rodent studies
Additionally, a meta-analysis of 46 randomized trials, including 171,244 participants, found that supplemental vitamin E, singly or in combination with other antioxidants, did not significantly alter the risk of all-cause mortality (126)
If blood sugar symptoms occur (lightheadedness, shakiness), eat a small meal before or immediately after injection
Some patients may experience hunger-related sleep disruption as they adjust to decreased appetite and smaller portions
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