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Similarly, TB-500 has undergone extensive safety evaluation including human research trials showing safety at intravenous doses up to 1,260 mg equivalent, with no dose-limiting toxicities or serious adverse events attributable to the peptide in carefully controlled studies

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For most patients, the demonstrated benefits substantially outweigh known risks

doi: 10.1016/j.amjcard.2004.06.047

I. Schelleret al., Thymosin 4 is essential for thrombus formation by controlling the G-actin/F-actin equilibrium in platelets, Ferrata Storti Foundation (Haematologica), Aug. 2021. doi: 10.3324/haematol.2021.278537

Furthermore, the blend is commonly researched for its potential to support lean body mass maintenance and positive nitrogen balance