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Interestingly, we see marginal release of cytochrome c following 5FU and a transient dip in MOMP, but no enhanced difference in sensitivity to BH3-mimetics or increase in ATF4 expression or predicted activity in RNA-seq analysis (data not shown)

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In cardiogenic shock a meta-analysis from studies including 280 patients found that norepinephrine was associated with a significantly lower rate of death compared to dopamine (DeBacker et al, 2010)