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For a complete injection tutorial including site rotation and technique see our [semaglutide injection guide](/guides/semaglutide-injection-sites-abdomen-thigh-arm)
To administer via injection, clean the injection site with an alcohol swab, pinch the skin to create a fold, insert the needle at a 45-90 degree angle, slowly inject the solution, then withdraw and apply gentle pressure
Physio-pathological effects of alcohol on the cardiovascular system: its role in hypertension and cardiovascular disease
Q: Who should consider a B12 shot
Another study in the Journal of the American Medical Association notes that among those with diabetic nephropathy (loss of kidney function due to diabetes), combining vitamin B6 (25 mg) and folic acid (2.5 mg) (B-complex vitamin) with 1,000 mcg of oral B12 per day for six years increases the risk of cardiovascular events, including heart attack and stroke
Do not refrigerate unless instructed by the manufacturer
