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Metabolic and cardiometabolic markers that may reflect the drug's activity include: Fasting blood glucose and HbA1c (particularly relevant in type 2 diabetes) Lipid profile (total cholesterol, LDL, triglycerides) Blood pressure Waist circumference Liver function tests, particularly in patients with metabolic dysfunction-associated steatotic liver disease (MASLD, previously termed NAFLD)

Within a few years, patients and clinicians will have a menu of options ranging from single-receptor oral pills to triple-receptor injectable agonists, each with distinct efficacy, safety, and convenience profiles

This slower transit time allows the intestines to absorb more water from the stool, resulting in firmer and drier stools that may be difficult to pass

In addition to reverse cholesterol transport, apoA-I can remove oxidized phospholipids from oxidized LDL (oxLDL) and from cells

Cardiovascular Protective Mechanisms of GLP-1 Receptor Agonists and Their Independence from Weight Loss