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Activation of GLP-1R can inhibit apoptosis and inflammation by stimulating phosphoinositide 3-kinase (PI3K) and protein kinase A (PKA) [23]
Twice-daily exenatide (Byetta) requires more specific timing: it should be administered within 60 minutes before the two main meals of the day (typically breakfast and dinner), at least 6 hours apart
If you develop signs of a severe allergic reaction such as swelling of the face, lips, or throat, difficulty breathing, or a widespread rash call 999 immediately
Diabetic retinopathy: Rapid blood sugar improvements can temporarily worsen vision in patients with diabetes
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Ensure electrolytes (sodium, potassium, magnesium)
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