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Limited research has examined the possible side effects of injecting lipotropic agents
Conversely, Hantson and coworkers [83] recently reported the case of a 47-year-old epileptic man in whom parenteral VPA therapy was associated with a severe hyperammonaemic encephalopathy (peak ammonia concentration 411 mol/l) without any biological signs of hepatotoxicity
Although melatonin treatment was associated with reduced GLUT1 expression ( Figure 5J ), this did not translate into a functional deficit in glucose uptake, as melatonin-treated cells displayed comparable 2-NBDG uptake to controls ( Figure 5K )
Some researchers believe that these substitutions confer increased potency, receptor interaction efficiency, and an extended period during which the peptide might remain active in a controlled research setting
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