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Plateaus in GH-related outcomes (body composition, recovery markers) after 46 weeks are common as the body adapts
This mechanism of action is responsible for the reduction of the lipid deposits in the blood vessels, which may diminish the risk of atherosclerosis
Outcomes for the first key question were the weight-related indicators [the absolute change and percentage change of body weight, change in BMI and waist circumference, weight loss targets (5%, 10% and 15%) from the baseline to the end of intervention]